Skin Longevity: Taking Care of Your Skin for the Long Run Learn more
With numerous bio-regenerative injectables available, it can be challenging to navigate the options and determine which treatment is best suited to your needs. This guide will help you by summarising the benefits and considerations of the most commonly used bio-regenerative injectables, including trout-derived polynucleotides (PN), salmon-derived polynucleotides (PN), collagen-stimulating skinboosters (PDLLA) and bio-remodelling HA.
Whether your goal is to smooth out wrinkles, hydrate your skin, increase firmness, or enhance tone and elasticity, there’s a treatment that can help you achieve your desired results and restore a youthful glow to your skin!

Polynucleotides are powerful bio-regenerative treatments that help restore skin health by repairing damaged skin, regenerating collagen, and strengthening the skin barrier. These injectables are derived from marine DNA—trout or salmon—and are designed to enhance hydration, elasticity, and skin resilience.
The main difference is their origin: PN from trout fish is sourced from Italy, while PN from wild salmon comes from South Korea.
Collagen-stimulating skinboosters combine Poly D-L-lactic acid (PDLLA) with Hyaluronic Acid (HA) to provide dual benefits: immediate hydration and long-term collagen stimulation. These injectables are particularly beneficial for those looking to rejuvenate the skin, reduce wrinkles and improve elasticity.
Bio-remodelling HA is an injectable treatment primarily composed of high concentrations of pure Hyaluronic Acid (HA). Unlike traditional fillers, it is designed to deeply hydrate and remodel the skin’s structure, enhancing overall skin quality.
Skinboosters are designed to target fine lines and dry skin, acting like a superficial filler to enhance hydration and texture. While not classified as bio-regenerative treatments, they improve skin quality using hyaluronic acid to attract and retain moisture.
Bio-regenerative treatments like trout-derived polynucleotides, salmon-derived polynucleotides and collagen-stimulating skinboosters (PDLLA) focus on collagen production and skin repair. Bio-remodelling HA shares hydration and rejuvenation goals with skinboosters but also restructures and firms the skin. Both enhance skin health.
When deciding which bio-regenerative injectable is best for you, consider your skin’s specific needs and your desired outcomes:
Each individual’s skin is unique, and the best way to determine the right treatment for your needs is through a consultation with our doctors. They can assess your skin’s condition, discuss your goals and recommend the most suitable injectable for optimal results.
By understanding the different types of bio-regenerative injectables and their benefits, you can take the first step toward fresh and healthy skin. Your journey to rejuvenation starts with choosing the right treatment for you.
Rest assured that regardless of your choice, our highest priority is to help you achieve satisfactory results that you will love. Our team is here to support you every step of the way. Contact us today to start your journey towards the results you desire.
* Per MOH guidelines, prescription-only medicines and professional-use-only medical devices must be referred to by their generic terms.